Cyclosporine:
Cyclosporine is an immunosuppressive drug derived from natural sources.
In the treatment of the SARS-CoV-2 certain studies suggest that the
Cyclosporin affects the molecular mechanism of SARS-CoV-2. De Wilde et
al. indicates that the siRNA block of the replication of RNA and protein
synthesis, thus inhibiting protein synthesis. Therefore, it evident that
the cyclosporin can be a potential treatment against
SARS-CoV-245. Pandey et al. stated that the
cyclosporine potentially prevents the cytokine storm, thus preventing
organ damage due to the excessive release of
cytokines41. However, clinical evidence for the
utility of Cyclosporin has not enough supportive evidence to be used as
an effective remedy.