Convalescent plasma
Passive immunity is the administration of antibodies against an
infective organism for the purpose of prevention and treatment of the
disease caused by that agent. Passive immunity has a long-standing
history before the development of antimicrobial therapy in the 1940s.
However, for certain infections that do not require respondents to
antimicrobial therapy, passive immunity is still used for such diseases.
An adequate quantity of antibodies must be administered to achieve
effective results of the therapy. The protection given by this antibody
to the patient depends upon the concentration of the antibodies given
and may last for weeks or months. The effectiveness of the sera varies
with the type of virus. COVID-19 is an example of such a disease. In the
meantime, plasma therapy is used as the best treatment for SARS-COV-2.
Experimental studies show that patients with consolidation, extensive
lung lesions, Sjogren syndrome, and GGO (GROUND-GLASS OPACIPICATION)
treated with plasma therapy discharged healthy from the
hospital[55]. According to the study convalescent
plasma can be used to prevent diseases among those who are exposed to
COVID-19 patients and to treat a patient with early
symptoms[24]. However, little information is
available on this topic, and fewer patients are used for clinical
trials, so more studies and trials are needed.