SE, standard error

HD, as a common alternative treatment for ESRD patients, can prolong the survival time of patients. Nevertheless, the high incidence of cardiovascular disease, such as heart failure and coronary heart disease, is the main cause of death. [7] Studies have shown the relationship between increased LA size, volume, and major cardiovascular events in ESRD [8]. There are many data available indicating that the diastolic function of ESRD is damaged earlier than the change of LV systolic function, and the change of LA function can more sensitively reflect the change of diastolic function. [9] The LA function can directly reflect the changes of atrioventricular pressure difference, which is the direct embodiment of left atrial preload and afterload. Thus, early detection of left atrial structural and functional impairment is helpful for the selection of clinical treatment options in the ESRD with preserved ejection fraction on HD. In the present study, we demonstrated that LA dimension and volume increased in ESRD compared to normal healthy groups, but the strain is lower. Additionally, the strain parameters showed a better correlation with LV diastolic filling pressure than conventional parameters.