More than 2-fold increase in anaphylaxis incidence between 2009 and 2019
Between 2009 and 2019, there were a total of 2,854 patients admitted 2,961 times with a physician-reported diagnosis of anaphylaxis over the span of 11 years. Detailed breakdown of the demographics, admissions and rates of AAI prescriptions of patients per year is shown in Table 1. The number of admissions (per geographical locations) and proportion of patients discharged with AAI per year are displayed in Figure 1. The overall 10-year estimated incidence rate was 3.57 per 100,000 person-years; the male to female ratio was 0.52 and the median age was 46 years (range 0-98 years). The estimated incidence rates per year are shown in Table 2. The increase in the anaphylaxis incidence rates was more than 2-fold from 2009 to 2019, with a particularly marked increase between 2013 and 2014 (2.80 to 4.44 per 100,000 population, respectively). The increased incidence was also much greater among the paediatric population (pediatric vs adult: 2.11 vs 2.30 per 100,000 population in 2009 to 7.40 vs 4.18 per 100,000 population in 2019).