INTRODUCTION
Intestinal tuberculosis (ITB) and Crohn’s disease (CD) are similar chronic granulomatous diseases making a real diagnostic problem.1, 2 Gastrointestinal tuberculosis is responsible for significant morbidity and mortality but can be cured with anti-tuberculosis chemotherapy for 6 months. Its frequency is estimated at 3-5%.2, 3 Crohn’s disease is a chronic disease that progresses over time and requires lifelong treatment to maintain remission. It has a high prevalence in industrialized countries but rare in Africa, especially in Sub-Saharan Africa.3, 4 It is notoriously difficult to differentiate ITB from CD, due to the similarity between the two pathologies from a clinical, radiological, endoscopic and even histopathological point of view.1, 3 Confusion between these two diseases can lead us to erroneously prescribe corticosteroid therapy. This can worsen the symptoms of tuberculosis (TB) and promote the development of complications.5-7 The elimination of ITB before the initiation of immunosuppressive therapy remains fundamental in the event of inflammatory ileo-colitis. Our objective is to report two cases of disseminated TB with digestive involvement revealed following corticosteroid therapy in order to alert our colleagues in endemic areas to the dangerousness of initiating corticosteroid therapy without formally ruling out ITB.