3.3 Effect of Molecular Weight
The antiviral activity shown by the different heparins appeared to
correlate broadly with their molecular weight. Overall UFHs with the
highest molecular weights ranging between 12,500 – 16,300 Da were more
potent inhibitors of SARS-CoV-2 than low molecular weight heparins
ranging between 4230 - 6,630 Da. Of the LMWHs the brand with highest
molecular weight Innohep (6,630 Da) had the highest antiviral effect
whereas Clexane (lowest molecular weight, 4,230 Da) had the weakest
antiviral effects.