2.9. Statistical analysis
Data are reported three times as the mean ± standard deviation. The data were analyzed statistically employing a one-way analysis of variance (ANOVA) using GraphPad PRISM® 8.0 software and p -values < 0.05 indicate statistically significant differences. The miRNA sequencing raw data were normalized based on the DESEQ normalized expression data. KEGG molecular pathway enrichment was reported where FDR was less than 0.001.