Key Message
The novelty and strength of our study were to show the efficacy and perceived satisfaction of 3-year SLIT via a real-life design. Despite the presence of robust evidence, very sparse data are available on the efficacy and perceived satisfaction of SLIT on selected patients inĀ real-life . We strongly believe that real-world studies, using data collected in everyday clinical settings, can hold the promise of providing real data to maximize the applicability and generalizability of an intervention. Moreover, the possibility to collect and test everything, and not only data-driven, will give the chance to realize a model analyzing both internal andexternal data sources and understand the context and patient behaviour. Furthermore, it becomes crucial especially in the drug approval process. All these fine-grained health data will open the way for personalized medicine to satisfy the unmet needs of a broad range of patients who reflect the diversity of persons and not only those who volunteer for clinical trials or biobanks.