Patients with allergic rhinitis with or without asthma
Of the 70 patients, 6 subjects reported allergic rhinitis, 4/6 (75%) had moderate to severe intermittent allergic rhinitis, and 2/6 (25%) had moderate to severe persistent allergic rhinitis. 34 out of 70 experienced allergic rhinitis with asthma. With the exception of 2 patients, 32 out of 34 subjects (94.11%) reported moderate to severe intermittent allergic rhinitis.
At T3 a significant clinical improvement, expressed in terms of nasal and eye symptoms, was reported: T0: 7.7 ± 1.5 vs. T3: 2.4 ± 2.7 (p<0.01). In parallel, a significant decrease was found in disease severity (T0: 8/40 (20%) vs. T3: 0/40 (100%), p<0.01), rescue medication use (T0: 6.4 ± 2.7 vs. T3: 2.4 ± 3.2 (p<0.01)), and sleep disturbances (T0: 19/40 (47.5%) vs. T3: 9/40 (22%), p<0.01).
A significant improvement was also recorded in school performance: T0: 9/40 (22%) vs. T3: 2/40 (5%), p<0.01.
No significant changes were reported in frequency of symptoms (≤ 4 days/week or ≤ 4 weeks : T0: 26 (65%) or 14 (35%) vs. T3: 21 (52.5%) or 19 (47.5%); ≥ 4 days/week o ≥ 4 weeks : T0: 20 (50%) or 20 (50%) vs. T3: 28 (70%) or 12 (30%).