Immunotherapy
SLIT was performed using a preparation of carbamylated allergoid (LaisĀ®, Lofarma SpA, Milan, Italy), biologically standardised in allergenic units (AU, 1:1000 AU), prepared as orosoluble tablets (allergoid SLIT), and administered according to the recommendations by the manufacturer. The patients started with the maintenance 1000 AU dose, taken regularly twice a week for house-dust mites and 5 times a week for pollens.