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Higher environmental composite quality index score and risk of asthma and allergy in Northeast China
  • +8
  • Shen Zhang,
  • Yu He,
  • Hong Liang,
  • Jie Gao,
  • Yinbang Li,
  • Yahong Li,
  • Lining Wang,
  • Xili Xie,
  • Ming Sun,
  • Changzheng Yuan,
  • Yanan Ma
Shen Zhang
Department of Biostatistics and Epidemiology, School of Public Health, China Medical University, Shenyang, Liaoning, P. R. China
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Yu He
Department of Biostatistics and Epidemiology, School of Public Health, China Medical University, Shenyang, Liaoning, P. R. China
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Hong Liang
Department of Biostatistics and Epidemiology, School of Public Health, China Medical University, Shenyang, Liaoning, P. R. China
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Jie Gao
Department of Biostatistics and Epidemiology, School of Public Health, China Medical University, Shenyang, Liaoning, P. R. China
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Yinbang Li
Department of Biostatistics and Epidemiology, School of Public Health, China Medical University, Shenyang, Liaoning, P. R. China
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Yahong Li
Department of Biostatistics and Epidemiology, School of Public Health, China Medical University, Shenyang, Liaoning, P. R. China
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Lining Wang
Department of Biostatistics and Epidemiology, School of Public Health, China Medical University, Shenyang, Liaoning, P. R. China
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Xili Xie
Department of Biostatistics and Epidemiology, School of Public Health, China Medical University, Shenyang, Liaoning, P. R. China
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Ming Sun
Department of Biostatistics and Epidemiology, School of Public Health, China Medical University, Shenyang, Liaoning, P. R. China
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Changzheng Yuan
Department of Big Data and Health Science, School of Public Health, Zhejiang University School of Medicine, Hangzhou, Zhejiang, P.R. China
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Yanan Ma
Department of Biostatistics and Epidemiology, School of Public Health, China Medical University, Shenyang, Liaoning, P. R. China
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Abstract

BACKGROUND Although evidence suggests a weak association of single environmental risk factors with asthma and allergy risk in children, the influence of a combination of multiple environmental pollutants and household air pollution in the relationship of asthma and allergy remains unclear. We aimed to assessed the association of environmental composite quality index scores with asthma and allergy. METHOD Environmental composite quality indices were collected using the questionnaire that contains asthma and allergy, Chinese residential living habits, and outdoor environment items. Multivariable odds ratios (ORs) and 95% confidence intervals (CIs) were estimated using the binary logistic regression model after adjusting the most known asthma or allergy risk factors. RESULTS In this cross-sectional study, a total of 1636 girls and 1446 boys were included in the final analyses. Higher environmental quality index score was correlated with higher risk of asthma, eczema, and rhinitis. Comparing the top (≥5) to bottom group (0-2), the multivariable ORs were 2.47 (95% CI, 1.41-4.33, P trend = 0.004) for asthma, 1.51 for eczema (95% CI, 1.18-1.93; P trend = 0.002) and 1.83 for rhinitis (95% CI, 1.12-3.00; P trend = 0.017). Similar findings were observed in the stratified analyses. CONCLUSION The study showed that there is a harmful association between environmental quality and asthma with allergic diseases in children living in northeast China, and further research was needed to confirm the findings in other areas and clarify the specific mechanism.