Corresponding Author
Kentaro Tamura
Division of Respiratory Diseases, Department of Internal Medicine, Atsugi City Hospital, Kanagawa, Japan
Address: 1-16-36 Mizuhiki, Atsugi, Kanagawa, 243-8538, Japan Tel: +81-46-221-1570 Fax: +81-46-294-3335 E-mail:kentaro.tamura.512@gmail.com
Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan
Address: 3-25-8 Nishi-Shimbashi, Minato, Tokyo, 105-8461, Japan
Abstract
This is a first observational study of four patients on steroid pulse therapy for secondary organizing pneumonia with respiratory failure due to the Coronavirus Disease 2019 (COVID-19) in our hospital. All patients needed invasive mechanical ventilation and had bimodal worseness of their respiratory status with organizing pneumonia after intubation. All cases could successfully discontinue oxygen therapy without any severe adverse events after this pulse therapy. Although few previous reports showed the efficacy and safety of this therapy, this therapy is believed to be effective on some optimal patients. Hence, further studies to explore this efficacy and safety were needed.