Corresponding Author
Kentaro Tamura
Division of Respiratory Diseases, Department of Internal Medicine,
Atsugi City Hospital, Kanagawa, Japan
Address: 1-16-36 Mizuhiki, Atsugi, Kanagawa, 243-8538, Japan
Tel: +81-46-221-1570
Fax: +81-46-294-3335
E-mail:kentaro.tamura.512@gmail.com
Division of Respiratory Diseases, Department of Internal Medicine, The
Jikei University School of Medicine, Tokyo, Japan
Address: 3-25-8 Nishi-Shimbashi, Minato, Tokyo, 105-8461, Japan
Abstract
This is a first observational study of four patients on steroid pulse
therapy for secondary organizing pneumonia with respiratory failure due
to the Coronavirus Disease 2019 (COVID-19) in our hospital. All patients
needed invasive mechanical ventilation and had bimodal worseness of
their respiratory status with organizing pneumonia after intubation. All
cases could successfully discontinue oxygen therapy without any severe
adverse events after this pulse therapy. Although few previous reports
showed the efficacy and safety of this therapy, this therapy is believed
to be effective on some optimal patients. Hence, further studies to
explore this efficacy and safety were needed.