References
1) Astrup K, Olivarius NDF. Frequency of spontaneously occurring postmenopausal bleeding in the general population. Acta ObstetGynaecolScand2004;83:203–7.
2) Moodley M, Roberts C. Clinical pathway for the evaluation of postmenopausal bleeding with an emphasis on endometrial cancer detection. J ObstetGynaecol 2004; 24:736.
3) The role of transvaginal ultrasonography in the evaluation of postmenopausal bleeding. ACOG Committee Opinion No. 734. American College of Obstetricians and Gynecologists. ObstetGynecol May 2018 - Volume 131 - Issue 5 - p e124–e129.
4) Goldstein RB, Bree RL, Benson CB, Benacerraf BR, Bloss JD, Carlos R, et al. Evaluation of the woman with postmenopausal bleeding: Society of Radiologists in Ultrasound-Sponsored Consensus Conference statement. J Ultrasound Med 2001;20:1025–36.
5) Smith-Bindman R1, Kerlikowske K, Feldstein VA, Subak L, Scheidler J, Segal M, Brand R, Grady D. Endovaginal ultrasound to exclude endometrial cancer and other endometrial abnormalities JAMA. 1998 Nov 4;280(17):1510-7.
6) Gredmark T, Kvint S, Havel G, Mattsson LA. Histopathological findings in women with postmenopausal bleeding. Br J ObstetGynaecol 1995 Feb;102(2):133-6.
7) Van den Bosch T, Ameye L, Van Schoubroeck D, et al. Intra-cavitary uterine pathology in women with abnormal uterine bleeding: a prospective study of 1220 women. Facts Views Vis Obgyn 2015; 7:17.
8) Robert J. Kurman, Lora Hedrick Ellenson and Brigitte M. Ronnett (Eds.) Blaustein’s Pathology of the Female Genital Tract Sixth Edition 2011 page 382.
9) Buckley C.H. and Fox H. (2002). The normal endometrium, as seen in biopsy material. In: Biopsy pathology of the endometrium. Second edition. Buckley C.H. and Fox H. (eds). Arnold. London. pp 27-42. ey CH, Fox H, eds. Biopsy pathology of the endometrium. 2nd ed. London: Arnold, 20.
10) Te Linde, R. W. (1940) Causes of postmenopausal bleeding. The American Journal of Surgery, 48, 289.
11) Novak, Edmund B Postmenopausal bleeding. June 1964 - Volume 7 - Issue 2 - ppg 464-475.
12) Dreisler E1, Stampe Sorensen S, Ibsen PH, Lose G. Prevalence of endometrial polyps and abnormal uterine bleeding in a Danish population aged 20-74 years. Ultrasound Obstet Gynecol. 2009 Jan;33(1):102-8.
13) Katherine M. Flegal, PhD1; Deanna Kruszon-Moran, MS1; Margaret D. Carroll, MSPH1; Cheryl D. Fryar, MSPH1; Cynthia L. Ogden, PhD1 Trends in Obesity Among Adults in the United States, 2005 to 2014 JAMA. 2016;315(21):2284-2291.
14) Laura Marczak, PhD; Kevin O’Rourke, MFA; Dawn Shepard, BA When and Why People Die in the United States, 1990-2013 JAMA. 2016; 315(3):241.
15) Frank P. Paloucek, MD; John B. Graham, MD; Clyde L. Randall, MD Benign Postmenopausal Vaginal Bleeding JAMA. 1967;199(10):701-703.
16) Schumamm E, Hyatt R Postmenopausal vaginal bleeding. Obstetrical & Gynecological Survey: August 1952 - Volume 7 - Issue 4 - ppg 544-546.
17) Kanter AE, Klawand AH. Postmenopausal bleeding. Urg Clin North Am. 1950 Feb;30(1):287-97.
18) Brzezinsky A, Bromberg YM Significance of postmenopausal genital bleeding in Jewish women. Obstet Gynecol. 1953 Mar;1(3):359-63.
19) Evans TN. Postmenopausal bleeding. Clin Obstet Gynecol. 1958 Sep;1(3):809-18.
20) Meyer WC, Malkasian GD, Dockerty MB, Decker DG. Postmenopausal bleeding from atrophic endometrium. Obstet Gynecol. 1971 Nov;38(5):731-8.
21) Rahn DD1, Carberry C, Sanses TV, Mamik MM, Ward RM, Meriwether KV, Olivera CK, Abed H, Balk EM, Murphy M. Vaginal estrogen for genitourinary syndrome of menopause: a systematic review. Obstet Gynecol. 2014 Dec;124(6):1147-56.
22) Ferenczy Pathophysiology of endometrial bleeding Maturitas 2003 May 30;45(1):1-14.
23) Berek & Novak’s gynecology (14th ed. Berek, Jonathan S. Lippincott Williams & Wilkins, 2007. page 1349. Table 33.3: Causes of Postmenopausal Bleeding.
24) http://www.uptodate.com/contents/postmenopausal-uterine-bleeding#H19.
25) http://www.aafp.org/afp/1999/1001/p1371.
26) http://www.webmd.com/menopause/guide/postmenopausal-bleeding.
27) Jeffrey B. Halter, Joseph G. Ouslander et al’ Hazzard’s Geriatric Medicine and Gerontology, 7e Gynecologic Disorders Table 42-4: Differential diagnosis of vaginal bleeding in older women.
28) https://www.health.harvard.edu/womens-health/abnormal-uterine-bleeding-in-peri-and-postmenopausal-womenPublished: January, 2011.
29) Ortiz ME1, Croxatto HB. Copper-T intrauterine device and levonorgestrel intrauterine system: biological bases of their mechanism of action. Contraception. 2007 Jun;75(6 Suppl):S16-30. Epub 2007 Mar 29.
30) American College of Obstetricians and Gynecologists. ACOG Practice Bulletin No. 121: Long-acting reversible contraception: Implants and intrauterine devices. Obstet Gynecol. 2011 Jul;118(1):184-96.
31) Maruti Sinha, 1 Rekha Rani,2 Ridhima Gupta,3 Kishan Chand,4 and Gurcharan Kaur5 Lippes Loop Inserted 45 Years Back: The Dilemma to Remove It or Leave It in situ. A Case Report with Review of Literature Clin Diagn Res. 2015 Apr; 9(430).
32) Cicinelli E, De Ziegler D, Nicoletti R, Colafiglio G, Saliani N, Resta L, Rizzi D, De Vito D. Chronic endometritis: correlation among hysteroscopic, histologic, and bacteriologic findings in a prospective trial with 2190 consecutive office hysteroscopies. Fertil Steril 2008;89:677 – 684.
33) Garuti G1, Sambruni I, Colonnelli M, Luerti M. Accuracy of hysteroscopy in predicting histopathology of endometrium in 1500 women. J Am Assoc GynecolLaparosc. 2001 May;8(2):207-13.
34) Ohad Rotenberg, MD, Malte Renz, MD, PhD, Laura Reimers, MPH, Georgios Doulaveris, MD, Juliana Gebb, MD, Gary L. Goldberg, MD, and Pe’er Dar, MD . Simultaneous endometrial aspiration and sonohysterography for the evaluation of endometrial pathology in women aged 50 years and older. ObstetGynecol 2015 Feb; 125:414.
35) Astrup K1, OlivariusNde F, Møller S, Gottschau A, Karlslund W. Menstrual bleeding patterns in pre- and perimenopausal women: a population-based prospective diary study. Acta ObstetGynecol Scand. 2004 Feb;83(2):197-202.
36) Astrup K1, OlivariusNde F. Frequency of spontaneously occurring postmenopausal bleeding in the general population. Acta ObstetGynecol Scand. 2004 Feb;83(2):203-7.
37) Burbos N1, Musonda P, Giarenis I, Shiner AM, Giamougiannis P, Morris E, Nieto JJ Age related differential diagnosis of vaginal bleeding in postmenopausal women: a series of 3047symptomatic postmenopausal women. Menopause Int. 2010 Mar;16(1):5-8.
38) JoAnn E. Manson, MD, DrPH Overview on menopause. Chapter 1 page 4. http://www.menopause.org/docs/2012/cg_a.pdf Chapter 1 page 4.
39) Magos AL, Brincat M, Studd JW, Wardle P, Schlesinger P, O’Dowd T. Amenorrhea and endometrial atrophy with continuous oral estrogen and progestogen therapy in postmenopausal women. Obstet Gynecol. 1985 Apr;65(4):496-9.
40) Epstein E1, Ramirez A, Skoog L, Valentin L. Dilatation and curettage fails to detect most focal lesions in the uterine cavity in women with postmenopausal bleeding. Acta ObstetGynecol Scand. 2001 Dec;80(12):1131-6.
41) Ferrazzi E, Torri V, Trio D, Zannoni E, Filiberto S, Dordoni D. Sonographic endometrial thickness: a useful test to predict atrophy in patients with postmenopausal bleeding. An Italian multicenter study. Ultrasound ObstetGynecol1996;7:315–21.
42) Geels YP1, Pijnenborg JM, van den Berg-van Erp SH, Bulten J, Visscher DW, Dowdy SC, Massuger LF. Endometrioid endometrial carcinoma with atrophic endometrium and poor prognosis. Obstet Gynecol. 2012 Nov;120(5):1124-31.
43) N. van Hanegem, M.C. Breijer, S.A. Slockers, M.H. Zafarmand, P.M.A.J. Geomini, R. Catshoek, J.M.A. Pijnenborg, L.F. van der Voet, F.P.H.L.J. Dijkhuizen, G.C.R. van Hoecke, N. Reesink-Peters, S. Veersema, M.H.A. van Hooff, P.J.M. van Kesteren, J.A. Huirne, B.C. Opmeer, M.Y. Bongers, B.W.J. Mol, A. TimmermansDiagnostic workup for postmenopausal bleeding: a randomised controlled trial. BJOG. 2017 Jan;124(2):231-240. doi: 10.1111/1471-0528.14126. Epub 2016 May 26.
44) Bansal N1, Herzog TJ, Burke W, Cohen CJ, Wright JD. The utility of preoperative endometrial sampling for the detection of uterine sarcomas Gynecol Oncol. 2008 Jul;110(1):43-8.
45) Obstetrics and Gynaecology: an evidence-based guide 2nd Edition Chapter 19 page 257.
46) ACOG: Frequently asked questions. Perimenopausal bleeding and bleeding after Menopause. https://www.acog.org/~/media/For%20Patients/faq162.pdf. November 2018.
47) http://www.webmd.com/menopause/guide/postmenopausal-bleeding.
48) RACGP: The women with postmenopausal women bleeding. Reprinted from Australian Family Physician Vol. 36, No. 3, March 2007
49) Otify M, Fuller J, Ross J, Shaikh H, Johns J. Endometrial pathology in the postmenopausal woman – an evidence based approach to management. The Obstetrician & Gynaecologist 2015;17:29–38.
Figure 1-Depicts a reroverteduterus with a fundal endometrial polyp. The catheter tip (marked by arrows) is sampling the anterior endometrium and missing the polyp.