Synthesis of results
Pregnancy prolongation :
Eight studies compared the difference in prolongation of pregnancy from study entry to delivery between women treated with pravastatin and women not treated. Pravastatin treatment was associated with a significant prolongation of pregnancy from study entry to delivery of 0.44 weeks (mean difference 0.44 weeks, 95%CI:0.01-0.87, p=0.04, I2=96%) (Figure 2).