Results
Clinical outcomes
There were no perioperative deaths or myocardial infarctions in the
presented groups. Median values of maximum troponin-I serum level were
1.05mcg/L (0.62-6.89mcg/L) in the OB group, and 1.3mcg/L
(0.97-3.41mcg/L) in the nOB group (ns). The mean number of performed
grafts were 2,2 +/- 0,6 (93+/- 7% revascularization rate). A two-year
follow-up (897 +/- 123 days) (29.9 +/- 4.1 months) was completed for 48
individuals (96%) and revealed 96% survival rate without episodes of
documented myocardial infarctions.
Blood flow in arterial grafts
In the OB group, the median value of graft measurement blood flow
through RIMA was 6 mL/min (4-13) with pulsation index (PI) of 3.3±1.3,
through LIMA – 10 mL/min (3-13) with PI of 3.1±1.2, and through RA –
2mL/min (2-11) with PI of 3.1±1.2, respectively.
In the nOB group, median flow through RIMA was 15 mL/min (8-27) with PI
of 3.1±1.4, through LIMA – 18mL/min (9-25) with PI of 3.1±1.0, and
through RA – 16 mL/min (14-34) with PI of 3.3±1.2, respectively. All
calculated medians of arterial grafts flow were significantly higher in
the nOB group and p value was 0.0043 for RIMA, 0.0023 for LIMA, and
0.0214 for RA (Figure 1).
Parameters of inflammation
Preoperative whole blood count data including two commonly accepted
indices of inflammatory reaction, platelet-to-lymphocyte ratio (PLR) and
neutrophil-to-lymphocyte ratio (NLR), are presented in Table 1. These
two parameters were significantly higher in the OB group.
GRAFT FLOW and NLR
Higher values of NLR were associated with lower blood flow. Even more
interestingly, a significant (p<0.05) although moderate
positive correlation was found between BMI and the aforementioned
inflammation indices (Figures 2 and 3), and a negative one between BMI
and LAD diameter (r=-0.34). Additionally, a significant
(p<0.05) yet also only moderate negative correlation (r=-0.33)
was noted between LAD diameter at the site of anastomosis and PLR.