2.2 Allergic fungal sinusitis (AFS) in children.
AFRS is also present in the paediatric age group and it should be considered as a differential in children presenting with nasal polyposis along with the other causes like ciliary dysmotility disorders and cystic fibrosis(70). There is paucity of data in literature regarding nature, clinical course and its recurrence in children and it was not possible to perform a qualitative analysis. Patro et al.(71) in a single centre prospective study compared features of AFRS in children to adults. The authors concluded that AFRS was more aggressive in children with increased fungal load when compared to adults. The serum IgE levels were also found to be significantly higher in paediatric group, suggesting a higher fungal load, with increased sensitivity to fungal antigen in children. Typically, AFRS in children was less responsive to treatment, with increased recurrence rates.