Anticoagulation during ablation
Intraablation anticoagulation was performed on the basis of the current
guidelines [3]. An initial heparin bolus of 120 units/kg was
intravenously administered immediately after the sheath insertion,
followed by its continuous infusion of 30-50 units/kg/h. Additional
heparin boluses were repeated to achieve an activated clotting time
(ACT) of 300-350 sec, if necessary. The ACT was checked at 15-minute
intervals until its target value was achieved, and then at 30-minute
intervals for the duration of the procedure. A 20-40 mg dose of
protamine was routinely infused to reverse the heparin at the end of the
procedure.