Age, years |
52 (45-62) |
57 (44-65) |
0.38 |
Male gender, n (%) |
33 (55.9) |
38 (55.9) |
1.00 |
BMI, kg/m2
|
29.2 (27.2-32.8) |
28.7 (26.5-33.5) |
0.76 |
Time from disease onset to enrollment, days |
9 (7-12) |
8 (5-11) |
0.12 |
Persistent fever, n (%) |
48 (81.4) |
43 (63.2) |
0.03 |
CRP>50 mg/L, n (%) |
30 (50.8) |
65 (95.6) |
<0.01 |
Comorbidities, n (%) |
|
|
|
Hypertension |
27 (45.8) |
32 (47.1) |
1.00 |
Diabetes |
11 (18.6) |
11 (16.2) |
0.82 |
Obesity |
16/42 (38.1) |
22/49 (44.9) |
0.53 |
History of stroke |
2 (3.4) |
1 (1.5) |
0.60 |
History of myocardial infarction |
3 (5.1) |
2 (2.9) |
0.66 |
Malignancy |
3 (5.1) |
2 (2.9) |
0.66 |
COPD |
1 (1.7) |
2 (2.9) |
1.00 |
Other* |
26 (44.1) |
32 (47.1) |
0.86 |
Oxygen saturation, % |
95 (94-96) |
94 (94-95) |
<0.01 |
Extent of lung involvement on CT, n (%) |
|
|
|
0-24% |
10 (16.9) |
2 (2.9) |
0.01 |
25-49% |
41 (69.5) |
22 (32.4) |
<0.01 |
50-74% |
8 (13.6) |
32 (47.1) |
<0.01 |
≥75 |
0 |
6 (8.8) |
0.03 |
Missing data |
0 |
6 (8.8) |
0.03 |
Body temperature (axillary), °C |
38.0 (37.5-38.5) |
37.4 (37.0-38.3) |
<0.01 |
Blood parameters |
|
|
|
White cells, ×109/L |
5.3 (4.3; 6.5) |
6.1 (4.8; 8.1) |
0.05 |
Neutrophils, ×109/L |
3.5 (2.7; 4.8) |
4.3 (3.2; 6.2) |
0.27 |
Lymphocytes, ×109/L |
1.1 (0.8; 1.6) |
1.2 (0.8; 1.5) |
0.71 |
CRP, mg/L |
53.0 (35.6; 87.6) |
79.2 (60.3; 155.0) |
<0.01 |
LDH, U/L |
479.0 (406.0; 615.8) |
608.0 (489.0; 792.5) |
0.01 |
Creatinine, mcmol/L |
96.5 (84.5; 110.0) |
98.9 (84.8; 110.1) |
0.58 |
Concomitant therapy, n (%) |
|
|
|
Antimalarials |
45 (76.3) |
60 (88.2) |
0.10 |
Lopinavir-ritonavir |
5 (8.5) |
9 (13.2) |
0.57 |
Glucocorticoids |
33 (57.9) |
15 (22.1) |
<0.01 |
Azithromycin |
38 (64.4) |
53 (77.9) |
0.12 |
Other antibiotics |
35 (59.3) |
50 (73.5) |
0.13 |
Low molecular weight heparins |
56 (94.9) |
43 (63.2) |
<0.01 |