Figure 1. Protein expression in serum in different severity grades and ethnic groups.
(a) Volcano plot of expressed serum proteins in SJS, SJS/TEN (n=10) vs. TEN (n=6) at baseline (day 0). Protein expression was measured by OLINK high-throughput targeted proteomics (inflammation and immune response panels), as described in our manuscript. (b) Box plots showing the serum levels of CNTNAP2, the only protein differentially expressed between ethnic subgroups (African: n=1; Asian: n=5; Caucasian: n=10), at baseline (day 0).