II |
IgG or IgM |
|
Hemolytic anemia |
III |
IgG or IgM |
|
Serum sickness |
Type IVa |
Th1 (IFN-γ) |
Monocyte activation |
Eczema |
Type IVb |
Th2 (IL-4/IL-5) |
Eosinophilic inflammation |
Maculopapular
exanthema, Drug Rush with Eosinophilia and systemic symptoms
(DRESS) |
Type IVc
|
CTL Perforin/
Granzyme B
|
CD4/CD8 mediated killing of cells
|
Maculopapular exanthema
Toxic epidermal necrolysis
|
Type IVd |
T cells (IL-8) |
Neutrophil activation |
Acute generalized
exanthematic pustulosis (AGEP) |
Type IVe |
Th2 cells |
CD4/CD8 cell activation |
|