11   Mangas-Sanjuan V, Buil-Bruna N, Garrido MJ, et al. Semimechanistic cell-cycle type-based pharmacokinetic/pharmacodynamic model of chemotherapy-induced neutropenic effects of diflomotecan under different dosing schedules. The Journal of pharmacology and experimental therapeutics 2015;354(1):55–64. doi:10.1124/jpet.115.223776.