CONCLUSION
In conclusion, individuals with constipation had a 2.11-fold greater risk for atopic dermatitis compared with those without constipation. Constipated patients should be alert to the elevated risk of developing AD. Furthermore, clinicians should determine the condition of the bowels, including the intestinal microbiota, in patients with AD. The precise pathophysiological relationship between constipation and atopic dermatitis still requires further research.