Stable Weight ≥5% Weight Loss ≥5% Weight Gain P-Value
N=18,826 N=1,672 N=1,862
Recipient Characteristics
Recipient Age (years) 57 (47-63) 56 (46-63) 56 (45-62) <0.001
Female 5,142 (27.3%) 397 (23.7%) 413 (22.2%) <0.001
Race
White 12,427 (66.4%) 1,122 (67.5%) 1,124 (60.8%) <0.001
Black 3,930 (21.0%) 371 (22.3%) 505 (27.3%)
Hispanic 1,557 (8.3%) 132 (7.9%) 158 (8.5%)
Asian 693 (3.7%) 29 (1.7%) 50 (2.7%)
Other 115 (0.6%) 8 (0.5%) 12 (0.6%)
BMI at Waitlisting (kg/m2) 27.32 (4.82) 30.02 (5.24) 26.01 (4.39) <0.001
BMI at Transplant (kg/m2) 27.32 (4.81) 26.76 (4.64) 29.39 (4.84) <0.001
Recipient Blood Type
A 7,747 (41.2%) 595 (35.6%) 662 (35.6%) <0.001
AB 1,156 (6.1%) 67 (4.0%) 58 (3.1%)
B 2,878 (15.3%) 231 (13.8%) 240 (12.9%)
O 7,045 (37.4%) 779 (46.6%) 902 (48.4%)
Heart Failure Etiology
Non-Ischemic 9,775 (52.0%) 887 (53.1%) 1,037 (55.7%) <0.001
Ischemic 6,450 (34.3%) 528 (31.6%) 665 (35.7%)
Congenital 559 (3.0%) 50 (3.0%) 50 (2.7%)
Restrictive 695 (3.7%) 69 (4.1%) 31 (1.7%)
Valvular 257 (1.4%) 22 (1.3%) 16 (0.9%)
Hypertrophic 512 (2.7%) 57 (3.4%) 27 (1.5%)
Other 30 (0.2%) 5 (0.3%) 1 (0.1%)
Diabetes Mellitus 5,172 (27.6%) 503 (30.2%) 514 (27.6%) 0.076
Total Bilirubin (mg/dL) 0.98 (1.62) 0.99 (1.48) 0.86 (1.12) 0.006
Serum Creatinine (mg/dL) 1.23 (0.61) 1.24 (0.48) 1.24 (0.40) 0.94
Positive CMV Serology 10,514 (55.8%) 899 (53.8%) 1,072 (57.6%) 0.075
Transfusion on Waitlist 3,527 (19.3%) 608 (37.8%) 675 (37.5%) <0.001
Pretransplant Mechanical Ventilation 245 (1.3%) 15 (0.9%) 9 (0.5%) 0.004
Pretransplant Intensive Care Unit 6,148 (32.7%) 555 (33.2%) 235 (12.6%) <0.001
Intravenous Inotropes 7,078 (37.6%) 559 (33.4%) 320 (17.2%) <0.001
Pretransplant Intra-Aortic Balloon Pump 1,954 (10.4%) 154 (9.2%) 60 (3.2%) <0.001
Pretransplant Extracorporeal Membrane Oxygenation 253 (1.3%) 21 (1.3%) 1 (0.1%) <0.001
Ventricular Assist
None 10,729 (57.7%) 747 (45.2%) 413 (22.4%) <0.001
LVAD 7,329 (39.4%) 770 (46.6%) 1,379 (74.9%)
RVAD 35 (0.2%) 4 (0.2%) 3 (0.2%)
TAH 159 (0.9%) 58 (3.5%) 16 (0.9%)
LVAD + RVAD 330 (1.8%) 74 (4.5%) 31 (1.7%)
Transplant Characteristics
Sex Matched 14,267 (75.8%) 1,314 (78.6%) 1,468 (78.8%) <0.001
Race Matched 9,696 (51.5%) 861 (51.5%) 920 (49.4%) 0.22
HLA Matched 2,428 (12.9%) 231 (13.8%) 239 (12.8%) 0.56
ABO Matched 15,761 (83.7%) 1,448 (86.6%) 1,688 (90.7%) <0.001
CMV Matched 9,946 (53.1%) 857 (51.4%) 989 (53.5%) 0.40
Donor Distance (nautical miles) 101 (14-303) 102 (15-289) 86 (12-271) 0.004
Cold Ischemic Time (hours) 3.2 (2.4-3.8) 3.2 (2.5-3.8) 3.1 (2.4-3.8) 0.15
Days Listed 74 (21-230) 220 (91-504) 417 (212-758) <0.001