Conclusion:
By pooling the adjusted HR for minimize the influence of clinical
differences between CRT-P and CRT-D recipients, our work demonstrates an
association of additional ICD and a lower all-cause mortality,
especially in patients with ICM. CRT-D did not manifest a survival
benefits in patients with older age (≥75 years), NICM, or using for
primary prevention, which provides an implication in risk stratification
of patients. RCTs are still needed to explore the real effect of
additional ICD in mortality.