Patient demographics
In total, 26 eligible patients were enrolled with SYST onto the present study between March 2008 and November 2018, representing 20.6% of total 126 germ cell tumor diagnoses in the period. Patient characteristics were listed in Table1. Briefly, patients had a median age of 1.7 years (range, new born to 5 years). The male to female ratio was 11:15. The median AFP levels were 50,480 mg/L (range, 1,200-8,0300,000 mg/L) at diagnosis. The stage distribution was 3 patients with stage II, 11 with stage III, and 12 with stage IV tumors. In patients with stage IV, metastatic sites were lung alone in 6 cases, bone and lung in 3 cases, liver and lung in 2 cases and liver alone in 1 case (Table 1).