Figure Legends
Figure 1. The general linear model analysis evaluating the correlation between pNK cytotoxicity and RM. The estimated marginal means of pNK cytotoxicity was compared between the fertile control (green) and RM patients (blue).
Figure 2. Expression of cytotoxic molecules on the peripheral blood NK cells. (A) Representative flow cytometry images of NK cells. (B) The percentage of pNK cells in the fertile control and RM patients. (C) Representative flow cytometry images of granzyme B+, granulysin+, and perforin+ pNK cells. The percentage and MFI of granzyme B+ (D, G), granulysin+ (E, H), and perforin+(F, I) pNK cells in the fertile control and RM patients. Results are expressed as mean ± SD. The independent t test was used for group comparison. *P <0.05.
Figure 3. Expression of the activating receptors on the peripheral blood NK cells. (A) Flow cytometry images representing the expression of NKG2D, NKp30, and NKp46. The numbers indicate the percentage of the cells in the gate. The histograms shows the difference in the percentage and MFI of NKG2D+ (B, E), NKp30+ (C, F), and NKp46+ (D, G) NK cells between the fertile control and RM patients. Results are expressed as mean ± SD. The independent t -test was used to perform the comparison.
Figure 4. Expression of the inhibitory receptors of the peripheral blood NK cells. (A) Flow cytometry images representing the expression of CD158a and CD158b. The numbers indicate the percentage of the cells in the gate. The histograms show the difference in the percentage and MFI of CD158a+ (B, C) and CD158b+ (D, E) NK cells between the fertile control and RM patients. Results are expressed as mean ± SD. The independent t -test was used to perform the comparison. **P <0.005.