Scientific lessons to be shared for public health actions
The occurrence of SARS-CoV-2 is international public health issue (40-42), economic (43), and other concerns currently. Since the worlds’ population is terrorized in acquiring SARS-CoV-2, the need decreased to visit the health institutions; they are being suffered by non-COVID-19 diseases. A press release of the Federal Ministry of Health, Ethiopia, assuring this fact, in which the ministry of health expressed that the numbers of patient flow were decreasing. Also, there were privet and governmental health institutions closed the normal service because of the COVID-19 pandemic(44). Therefore, with the high transmission rate of SARS-CoV-2 while asymptomatic raises the public health practitioners should consider; one thing; serial virologic, serologic data, or a combination of both in observational cohorts or surveillance systems studies should be conducted to clarify the magnitude of asymptomatic infections of SARS-CoV-2. This can be used to compare numbers of asymptomatic and symptomatic infections; if asymptomatic cases are high proportion, it enhances disease detecting strategies. Second, if large proportions of SARS-CoV-2 is from asymptomatic infection, the effectiveness of public health interventions like physical distancing, contact tracing, quarantine of different group of populations, which are aimed to reduce the spread of infection(45) should be quantified. However, in the presence of different attitudes of people, the culture of populations, and economic status, it is very difficult to conclude contact tracing is a perfect prevention measure(36, 46). Therefore, if the COVID-19 pandemic is found to be ambitious by undetected asymptomatic SARS-CoV-2 infections, new innovations in disease detection and prevention may be needed to be introduced in each country. Last but not the least, knowledge of SARS-CoV-2 immunity among persons with asymptomatic or symptomatic infection is not still fully or partially studied. Immunity developed in these persons, how long protective immunity lasts, and if there will be reinfection, and if there will be carrier state are not well clarified(47). These types of evidences are vital for healthcare and other critical infrastructure workers; the answers to these questions will be decisive to decide relaxing of community interventions, resuming the normal functions of society, recovering from the COVID-19 pandemic, then after to make this disease be history as the previous pandemics.