Corona Virus Disease 2019 is an RNA virus that currently affecting more than 210 countries, more than 3,221,617 cases, and 228,263 deaths are reported till April 28, 2020. There is a knowledge gap regarding the incidence proportion of asymptomatic and symptomatic infection so that public health interventions can be reviewed. We searched the original articles in google Scholar for articles that were published from January 1 through May 5 2020, and country updated reports of coronavirus disease. Finally, reviewed to compile and make conclusions. Different epidemiologic studies support the possibility of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detected could able to transmit during the asymptomatic state. SARS-CoV-2 transmission in the absence of symptoms reinforces the value of measures that prevent the spread of SARS-CoV-2 by infected persons who may not exhibit illness despite being infectious. The existence of persons with asymptomatic SARS-CoV-2 infection who are capable of transmitting had many implications. The case-fatality rate for COVID-19 may be lower or inaccurate, reinforces the value of community interventions, and could enhance the need to increase the capacity for widespread testing and thorough contact tracing.