Conclusion and Implications
The experiments in the OA model verified the analysis results. With the help of the analysis strategy, the present study effectively and rapidly analyzes the active ingredients of HL treating OA. The example in this research also verifies the feasibility of this strategy, which is of reference significance to the related studies of other herbal medicines.
Keywords: bioinformatics; herbal medicines; active ingredients; Herba Lysimachiae; osteoarthritis
Abbreviations: CMC , carboxymethylcellulose; DSS , diclofenac sodium salt; ELISA , enzyme-linked immunosorbent assay; HL , Herba Lysimachiae; Itga2b , integrin alpha 2b; Itgb3 , integrin beta 3; MIA , monosodium iodoacetate; OA, osteoarthritis;