Conclusion and Implications
The experiments in the OA model verified the analysis results. With the
help of the analysis strategy, the present study effectively and rapidly
analyzes the active ingredients of HL treating OA. The example in this
research also verifies the feasibility of this strategy, which is of
reference significance to the related studies of other herbal medicines.
Keywords: bioinformatics; herbal medicines; active ingredients;
Herba Lysimachiae; osteoarthritis
Abbreviations: CMC , carboxymethylcellulose; DSS ,
diclofenac sodium salt; ELISA , enzyme-linked immunosorbent
assay; HL , Herba Lysimachiae; Itga2b , integrin alpha
2b; Itgb3 , integrin beta 3; MIA , monosodium
iodoacetate; OA, osteoarthritis;