Pathway Total Expected Hits P.Value FDR
Hematopoietic cell lineage 95 7.1 27 6.64E-10 1.46E-07
B cell receptor signaling pathway 72 5.38 23 9.83E-10 1.46E-07
Primary immunodeficiency 36 2.69 16 1.40E-09 1.46E-07
Protein processing in endoplasmic reticulum 163 12.2 30 3.07E-06 0.000241
T cell receptor signaling pathway 101 7.55 22 3.85E-06 0.000242
Calcium signaling pathway 189 14.1 30 6.11E-05 0.0032
NF-kappa B signaling pathway 109 8.14 20 0.000141 0.00607
Cell adhesion molecules (CAMs) 171 12.8 27 0.000155 0.00607
Epstein-Barr virus infection 230 17.2 33 2.00E-04 0.00696
Antigen processing and presentation 91 6.8 17 0.000351 0.011
Chemokine signaling pathway 200 14.9 29 0.000401 0.0114
AGE-RAGE signaling pathway in diabetic complications 101 7.55 18 0.000434 0.0114
Fc gamma R-mediated phagocytosis 87 6.5 16 0.000622 0.015
Leukocyte transendothelial migration 115 8.59 19 0.000808 0.0181
Leishmaniasis 67 5.01 13 0.00118 0.0232
Jak-STAT signaling pathway 165 12.3 24 0.00118 0.0232
HIF-1 signaling pathway 105 7.85 17 0.00188 0.0347
EGFR tyrosine kinase inhibitor resistance 80 5.98 14 0.00219 0.0382
Toxoplasmosis 108 8.07 17 0.00256 0.0418
Natural killer cell mediated cytotoxicity 118 8.82 18 0.00277 0.0418
Non-small cell lung cancer 66 4.93 12 0.00319 0.0418
Legionellosis 58 4.33 11 0.00333 0.0418
Arginine and proline metabolism 50 3.74 10 0.00337 0.0418
ErbBsignaling pathway 84 6.28 14 0.00349 0.0418
Th17 cell differentiation 102 7.62 16 0.0035 0.0418
Focal adhesion 199 14.9 26 0.00355 0.0418
Pathways in cancer 535 40 57 0.00363 0.0418
Mucin type O-glycan biosynthesis 28 2.09 7 0.00372 0.0418
Intestinal immune network for IgA production 43 3.21 9 0.00387 0.0419
Cytokine-cytokine receptor interaction 296 22.1 35 0.00433 0.0453
Measles 144 10.8 20 0.00503 0.051
NOD-like receptor signaling pathway 206 15.4 26 0.00565 0.0539
Longevity regulating pathway - multiple species 62 4.63 11 0.00567 0.0539
GABAergic synapse 90 6.73 14 0.00658 0.0608
Pancreatic cancer 75 5.6 12 0.00917 0.0823
Glutamatergic synapse 114 8.52 16 0.0104 0.0899
Regulation of actin cytoskeleton 217 16.2 26 0.011 0.0899
Platinum drug resistance 77 5.75 12 0.0113 0.0899
Platelet activation 125 9.34 17 0.0114 0.0899
Prion diseases 34 2.54 7 0.0115 0.0899
Th1 and Th2 cell differentiation 87 6.5 13 0.012 0.0922
Rap1 signaling pathway 209 15.6 25 0.0127 0.0931
Glycosphingolipid biosynthesis - lacto and neolacto series 27 2.02 6 0.013 0.0931
Carbohydrate digestion and absorption 43 3.21 8 0.013 0.0931
Osteoclast differentiation 128 9.56 17 0.0142 0.0992
Axon guidance 180 13.5 22 0.0148 0.101
Protein digestion and absorption 90 6.73 13 0.0158 0.105
PI3K-Akt signaling pathway 358 26.8 38 0.017 0.111
MAPK signaling pathway 294 22 32 0.0196 0.126
Alanine, aspartate and glutamate metabolism 38 2.84 7 0.0208 0.13
Estrogensignaling pathway 134 10 17 0.0216 0.133
Sphingolipid metabolism 48 3.59 8 0.0245 0.148
Rassignaling pathway 233 17.4 26 0.0252 0.148
Amoebiasis 106 7.92 14 0.0257 0.148
Nicotine addiction 40 2.99 7 0.027 0.148
VEGF signaling pathway 58 4.33 9 0.027 0.148
Endometrial cancer 58 4.33 9 0.027 0.148
Glycosphingolipid biosynthesis - globo and isoglobo series 16 1.2 4 0.0273 0.148
Prostate cancer 97 7.25 13 0.0278 0.148
Renal cell carcinoma 68 5.08 10 0.0286 0.15
Inflammatory bowel disease (IBD) 59 4.41 9 0.0298 0.154
Fluid shear stress and atherosclerosis 143 10.7 17 0.0375 0.187
IL-17 signaling pathway 91 6.8 12 0.0376 0.187
Small cell lung cancer 92 6.87 12 0.0404 0.196
Adherens junction 72 5.38 10 0.0405 0.196
Cholinergic synapse 113 8.44 14 0.0415 0.197
Chagas disease (American trypanosomiasis) 103 7.7 13 0.0426 0.198
Sphingolipid signaling pathway 124 9.27 15 0.0428 0.198
Thyroid hormone signaling pathway 115 8.59 14 0.047 0.213
Gastric acid secretion 74 5.53 10 0.0475 0.213
Phagosome 181 13.5 20 0.0497 0.22