Study approval
All animal studies were performed in accordance with current European
(Directive 2010/63/EU) and National (Real Decreto 53/2013)
legislation for the Use and Care of Laboratory Animals, and according to
the ARRIVE Guidelines. The protocol was approved by the Instituto
de Investigación Sanitaria Fundación Jiménez Díaz (IIS-FJD) Animal
Research Ethical Committee and by the Comunidad de MadridCommittee (PROEX 065/18). All animal work took place in the Laboratory
of Molecular and Cellular Biology in Renal and Vascular Pathology of the
IIS-FJD at the Autónoma University of Madrid.