Phylogenetic analysis
The neighbor-joining phylogenetic tree in the Figure 1 shows a main clade containing 5 clusters. The viral genome sequence of the female 22 year aged Bangladeshi patients (GISAID accession ID: EPI_ISL_437912) was closely related to that of another 4 genome sample taken from the four different Asian countries (GISAID accession ID: EPI_ISL_430111; EPI_ISL_438966; EPI_ISL_425214; EPI_ISL_422227). These five genome sequences were located in a cluster A.1 with genomes mainly from Asia (Russia, Japan, Kuwait), but also one from Spain (Figure, highlighted in blue). In cluster A, six other six genomes mainly from Asian countries like Saudi Arabia (EPI_ISL_437762), Israel (EPI_ISL_435292), Turkey (EPI_ISL_437335), Myanmar (EPI_ISL_434709) and one from United Kingdom (GISAID accession ID: EPI_ISL_442502). Based on these comparisons, it can be predicted that the circulating Bangladeshi SARS-CoV-2 isolate published has phylogenetic relevance to some of the Asian countries as well as Spain. In the tree, some sequences from other SARS-CoV-2 collected in Asian countries segregated in separate clusters from the one cluster containing the respective Bangladeshi sequences characterized in this study. There was for example a cluster B formed by 8 sequences dominated by all Asian countries (Cambodia, Nepal, Malaysia, Pakistan, and Indonesia) except one from USA. This cluster B also contain the reference sequence from Wuhan, china (NC_045512.2). Cluster C contain 6 genome sequences followed by Cluster D (2 genome sequences). The two sequences (EPI_ISL_438138 and EPI_ISL_437438) retrieved from the neighboring country of Bangladesh, India, which covers almost all the direction except south (Bay of Bengal is in south) are in the cluster E (Figure 1).