Amelie Watelet

and 8 more

Yasmine Souala-Chalet

and 10 more

Objectives: To compare the neonatal morbidity of caesarean sections (CS) performed after conversion from neuraxial (NA) to general anaesthesia (GA) with CS performed under GA from the outset, and to assess whether the increase in DDI in urgent and extremely urgent cases with conversion from NA to GA increased the risk of neonatal morbidity. Design: Retrospective cohort study. Setting: University-affiliated hospital. Population: All CS performed under GA between 2015 and 2019. Methods & main outcome measures: Our main criteria used for assessing neonatal morbidity were: neonatal pH <7.10 and/or an Apgar score at 5 minutes <7. A multivariate regression analysis was performed to adjust for gestational age, birth weight, indication of CS. Results: We included 284 patients: 116 had a conversion from NA to GA (group 1) and 168 had GA from the outset (group 2). There was no significant difference in the rate of neonates having a pH<7.10 and/or Apgar score <5 between groups 1 and 2 (17.5% Vs 26.3%, p=0.08, respectively). Multivariate analysis showed that neonatal morbidity was comparable between the two groups (OR=1.58; 0.83-3.05). In very urgent CS, the mean decision-to-delivery interval (DDI) was 3 minutes longer in group 1 compared to group 2 (17 min vs 14 min, respectively), and there was no significant difference in neonatal pH and/or Apgar <7 at 5 minutes between the two groups (aOR=1.4; 0.5-4.3). Conclusion: The neonatal outcomes were comparable between CS performed after conversion from NA to GA and under GA from the outset, even in very urgent CS.

Sebastien Madzou

and 11 more

Objectives: To investigate the perinatal outcomes of women with a history of female genital mutilation (FGM) who underwent clitoral reconstruction (CR) compared with women with FGM who did not undergo CR. Design: Retrospective case-control study Setting: Angers University Hospital, between 2005 and 2017 Methods: Inclusion criteria: pregnant women >18 years who underwent CR after FGM. Only the first subsequent delivery after CR was included. Each woman with CR was matched for age, ethnicity, FGM type, parity, and gestational age at the time of delivery with two women with FGM who did not undergo CR during the same period of time. Main outcome measures: at birth: need for episiotomy and intact perineum Results: 84 women were included (28 in the CR group; 56 in the control group). In the CR group, patients required significantly fewer episiotomies (5/17[29.4%]) compared to the control group (28/44[63.6%], p=0.02), even after excluding operative vaginal deliveries (2/13[15.4%] vs 21/36[58.3], p<0.01). CR reduces the risk of episiotomy (aOR=0.15, 95%CI [0.04-0.56]; p<0.01) after adjusting on the infant weight and the need for instrumental delivery. In the CR group, 47% of the patients had an intact perineum after delivery, compared to 20.4% in the control group (p=0.04). CR increases the odds of having an intact perineum at birth by 3.46 times (CI95%[1.04-11.49]; p=0.04). Conclusion: CR after FGM increases the chances of having an intact perineum after delivery by 3.46 times and reduces the risk of episiotomy by 0.15 times compared to women with FGM who did not underwent CR.