Pharmacology of Remdisivir
Remedisivir, an adenosine analogue, incorporates itself into viral RNA chains resulting in pre-mature termination [3]. It has been described as a potential antiviral medication against a broad variety of RNA viruses, including SARS and MERS, in animal models [4,5] . Remdisivir also inhibited virus infection in a human cell line that is susceptible to SARS-CoV-2 [6]. Remdesivir has also been shown to reduce viral load of MERS-CoV in the lung tissue of infected mice. Moreover, it enhanced lung function and reduced damage to the lung tissue. [7] Among the various therapeutic candidates, it showed success both in vivo and in vitro against coronaviruses in general. [8]