Randomization
The random sequence has generated using the Minitab
18® statistical program (version 18, Minitab, LLC,
State College, Pennsylvania, USA) by a researcher not involved in the
allocation of participants. Block randomization has used without
stratification and has implemented by an administrative assistant using
sequential numbering, sealed envelopes. Individuals in the argon arm
underwent three APC sessions, with an 8-week interval between them. The
endoscopic evaluation has performed every 2 months until completing 6
months. In the control group, the arm underwent an initial diagnostic
endoscopy followed by clinical consultation every 2 months until the
sixth month. All patients were blinded to the intervention they
received. The multidisciplinary team (nutritionist, psychologist, and
physical educator) and data analysts were also blinded to the allocation
of participants.