Limitations
Being a real-world retrospective observational analysis, our study lacks
the randomization of potential future trials. Second, our research
analyzed the populations of two high-volume nationwide referrals for VT
ablation, whose results may not be generalized to all centers due to
referral bias. Third, while PS matching is a viable tool for covariate
homogenization, we can’t guarantee the non-inclusion of other potential
confounding variables. Nonetheless, the verification of similar results
in the PS population strengthens its conclusions. Fourth, it was not
possible to access detailed information on the ventricular scars
(voltage maps or cardiac magnetic resonance imaging) in all patients. At
last, the choice of combined or non-combined strategy was done at the
operator’s discretion, which may create a nonobjectifiable bias.