Main findings
The paper describes the results on the first 65 cases of COVID-19 infection during pregnancy notified to the ItOSS, with the aim of providing rapid feedback for clinicians and policymakers. The cohort includes 10 women admitted for out or inpatient hospital care at ≤14 weeks of gestational age, 33 between 15 and 27 weeks and 21 ≥28 weeks. Women’s mean age is 33.8 years (SD=5.5) and 68,3% are multiparas. Forty-one per cent of the women developed a COVID-19 pneumonia, previous comorbidity being significantly associated (p-value 0.002). At hospital admission 10.8% of the women were asymptomatic, and almost 50% reported not having had risk contacts during the 14 days prior to symptom onset. Overall, cough, fever and general weakness are the most common reported symptoms. Dyspnoea affects 66.7% of the women with pneumonia that in over 81.5% received at least one pharmacological treatment. Overall, 18.6% of the women received invasive respiratory support, 3 women developed severe maternal morbidity and 3 were admitted to intensive care unit, none died.