3.5 Distinct characteristics of COVID-19 between younger and
older children
Given the physiological and immunological differences of younger and
older children, we divided the cases into two groups according to ages
and compared the clinical features and laboratory results of them (Table
S3 and S4). Children aged 10 years or older experienced more fatigue and
had more GGO lesions in chest CT images (p < 0.05), but there
remained more individuals to be further observed. The differences in
several laboratory parameters were likely to be induced by their own
changes with age, and the most results were in normal ranges without
clinical significance. In addition, there was no difference in the
prevalence of allergic diseases between the two age groups. Moreover,
there was no difference in the proportion of children with possible
co-infections, such as MP, between children <10 years and
children ≥10 years.