3.5 Distinct characteristics of COVID-19 between younger and older children
Given the physiological and immunological differences of younger and older children, we divided the cases into two groups according to ages and compared the clinical features and laboratory results of them (Table S3 and S4). Children aged 10 years or older experienced more fatigue and had more GGO lesions in chest CT images (p < 0.05), but there remained more individuals to be further observed. The differences in several laboratory parameters were likely to be induced by their own changes with age, and the most results were in normal ranges without clinical significance. In addition, there was no difference in the prevalence of allergic diseases between the two age groups. Moreover, there was no difference in the proportion of children with possible co-infections, such as MP, between children <10 years and children ≥10 years.