Primary outcomes
Using the Kaplan-Meier survival curve and the Cox-regression analyses,
we did not find any significant differences in mortality in the ACEI/ARB
group and non-ACEI/ARB group (P = 0.27; Table1; Figure 1A ).
Similar results found in the ARB group compared non-ARB group and ACEI
group compared to the non-ACEI group. The Kaplan-Meier survival curve
showed a trend of improved survival among patients treated with ARB when
compared with the group not treated with ARB (Figure 1B ). A
similar trend was observed by the multivariate regression analysis
(adjusted hazard ratio, 0.27; 95% CI, 0.07-1.02; P=0.054; Table
3 ). Using the Kaplan-Meier survival curve and the Cox-regression
analyses, we did not find any significant differences in mortality in
the ACEI group and the non-ACEI group (Figure 1B ; Table
3 ). The Kaplan-Meier survival curve and the Cox-regression analyses
showed a better survival in the ARB groups than the ACEI group (adjusted
hazard ratio, 0.03; 95% CI, 0.00-0.58; P=0.02; Figure 1C ;Table 2 and 3 ), although there was no significant difference of
the mortality rate between ACEI and ARB groups (P = 0.059; Table
2 and 3 ).