Funding:
This work was supported by the National Natural Science Foundation
(grants 81772046 and
81971816
to Dr. Peng) and the Special Project for Significant New Drug Research
and Development in the Major National Science and Technology Projects of
China (2020ZX09201007 to Dr. Peng).
Author Contributions : Drs Z. Peng, Q. Lu, and R. Liu designed
the study. L Su, J Zhang, N Jiang, J Li, J Yang, L He, Q Xie, R Huang, F
Liu, F Yuan, Y Feng, J Jiang, and R. Liu analyzed the data and performed
the statistical analyses. L. Su, R. Liu, J Yang, and J Li drafted the
initial manuscript. B, Kashani made a critical revision of the initial
manuscript.All authors reviewed the drafted manuscript for critical
content and approved the final version.