Primary outcomes
Using the Kaplan-Meier survival curve and the Cox-regression analyses, we did not find any significant differences in mortality in the ACEI/ARB group and non-ACEI/ARB group (P = 0.27; Table1; Figure 1A ). Similar results found in the ARB group compared non-ARB group and ACEI group compared to the non-ACEI group. The Kaplan-Meier survival curve showed a trend of improved survival among patients treated with ARB when compared with the group not treated with ARB (Figure 1B ). A similar trend was observed by the multivariate regression analysis (adjusted hazard ratio, 0.27; 95% CI, 0.07-1.02; P=0.054; Table 3 ). Using the Kaplan-Meier survival curve and the Cox-regression analyses, we did not find any significant differences in mortality in the ACEI group and the non-ACEI group (Figure 1B ; Table 3 ). The Kaplan-Meier survival curve and the Cox-regression analyses showed a better survival in the ARB groups than the ACEI group (adjusted hazard ratio, 0.03; 95% CI, 0.00-0.58; P=0.02; Figure 1C ;Table 2 and 3 ), although there was no significant difference of the mortality rate between ACEI and ARB groups (P = 0.059; Table 2 and 3 ).