Funding:
This work was supported by the National Natural Science Foundation (grants 81772046 and 81971816 to Dr. Peng) and the Special Project for Significant New Drug Research and Development in the Major National Science and Technology Projects of China (2020ZX09201007 to Dr. Peng).
Author Contributions : Drs Z. Peng, Q. Lu, and R. Liu designed the study. L Su, J Zhang, N Jiang, J Li, J Yang, L He, Q Xie, R Huang, F Liu, F Yuan, Y Feng, J Jiang, and R. Liu analyzed the data and performed the statistical analyses. L. Su, R. Liu, J Yang, and J Li drafted the initial manuscript. B, Kashani made a critical revision of the initial manuscript.All authors reviewed the drafted manuscript for critical content and approved the final version.