Financial support:
This study was partly supported by grants from the National Natural
Science Foundation of China (82102879), the Natural Science Foundation
of Guangdong Provence (2021A1515012518), the Postdoctoral Research
Foundation of China (2021M691468). The funding agencies had no role in
the study design, data collection and analysis, decision to publish, or
preparation of the manuscript.
PI statement: The authors confirm that the Principal
Investigator for this paper is Jinzhang Chen and that he has direct
clinical responsibility for the subjects.
Word count (abstract): 258; Word count (full text): 2339; Tables: 2;
Figures: 4; References: 29