Introduction
On December 31th, 2019, a group of pneumonia cases of unknown origin in the city of Wuhan in the Hubei Province in China was detected (1) which was later found out to be caused by a new emerging β-coronavirus, called 2019 novel coronavirus(2019-nCoV) or Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) (2). On February 8th, 2020 pneumonia caused by this agent was afterward named Novel Coronavirus Pneumonia (NCP) (3) which was later changed to Coronavirus infection disease 2019(COVID-19). COVID-19 starting in China, rapidly spread to other parts of the country and other nations (4) as well, with an exponential growth rate (5) so as until April 23rd, 2020 causing 2,544,792 confirmed cases and 175,694 deaths worldwide with the United States, Spain and Italy being affected the most (6). On January 30th, 2020 the world health organization declared a state of Public health emergency of international concern(PHEIC) for the sixth time (5), and on March 11th, 2020 WHO assessed COVID-19 as a pandemic (7). SARS-CoV-2 is an enveloped, single-stranded, positive-sense, zoonotic member of β-coronaviruses (4, 8)which are known for causing more severe and lethal disease (4) as in previous major epidemics like severe acute respiratory syndrome(SARS) and middle-eastern respiratory syndrome(MERS) (2). The first cases had a history of being in touch with seafood or animal wholesale markets which raised the suspicion of zoonotic transmission (9, 10), and bats were assumed to be the reservoir host (11). The virus has an incubation period of 1 to 14 days, which for most cases, an incubation period of 4 days has been reported (3, 5, 11) and can be transmitted through droplets, contaminated objects, and Human-to-Human contact whether being symptomatic or asymptomatic. COVID-19 confirmed cases are seen mostly among adults with children under 10 only accounting for 0.9% cases (12) and mostly being asymptomatic or having mild forms of the disease so having the capacity to act as carriers (1, 4). Patients mostly complain of fever, dry cough, and myalgia with associated laboratory and radiological findings. There is no specific treatment or vaccine for COVID-19 until now but several potential options under investigation. In this study we aim to have a look into potential pharmacologic treatment options for COVID-19.