4 SUMMARY LAYOUT AND
CONCLUSION
Like any other contagious disease, spread dynamic and disease burden of
the new pandemic of the highly contagious COVID-19 vary among different
populations. The COVID-19 outbreak has affected all aspects of human
life worldwide; hence, discussing the country to county variations of
the COVID-19 outbreak can help to take more effective measures to fight
against this new pandemic. According to the previously published
reports, it seems that the new COVID-19 is not as lethal as its
counterparts, i.e., SARS (Severe acute respiratory syndrome) and MERS.
However, the higher contagious nature of the COVID-19, followed by a
higher DR value of this pandemic, in comparison with the previous acute
to respiratory syndromes, has led to a more difficult situation these
days.
Considering the unique context of the Middle East, which can affect many
other countries in the world, in this research, we focused on discussing
any variations in the mortality-related epidemiological terms between
all the countries located in this region and the top ten most affected
countries worldwide. For this comparison, we did best to consider the
CFR, the DR, the CDR, and the RR values together and avoid any probable
bias. We also tried to benefit from the previously published reports.
Hence, a comprehensive literature review was performed, which helped a
lot to come to a better understanding of the data we obtained in this
research. In brief, our findings showed that, to the best of our present
knowledge, the key factors causing the tody’s country to country
variations, in terms of the epidemiological indicators of the COVID-19,
mainly originated from the significant cultural-ideological differences,
the enormous differences between the health systems of countries, and
the efficacy of the governmental mitigation policies.We also believe
that many biological factors, including the regional genetic profile,
age, sex, and immunological signature, can dramatically influence the
epidemiological variations of the COVID-19. However, there was no
sufficient information on this aspect at the time of this writing.