Figure legends
Figure 1. Physiological transcytosis of circulating LDLvia caveolae.
Figure 2. Overview of the main interactions occurring between oxLDL and caveolae and their impact on intracellular signaling in EC. ① LOX-1-mediated oxLDL uptake; ② oxLDL-induced HMGB1 release and TLR4 activation; ③ ox-LDL transcytosis; ④ oxLDL-mediated membrane cholesterol exchange, depletion, redistribution. Direct evidence , undirect evidence , hypothetical connection .