Statistical analysis
Statistical analysis of RNA sequencing count data was conducted using edgeR with a 5% FDR. All experiments were repeated at least three times and are presented as the mean±standard deviation and the median with interquartile range. Statistical analysis were assessed via Spearman correlation, Mann-Whitney test and one-way analysis of variance followed by Tukey’s test for multiple comparisons. p values < 0.05 were considered statistically significant.