Results
Eighty patients were identified with AoD. Table 1 presents population
characteristics of the forty-seven (47) patients with complete data who
met inclusion criteria. Thirty-five patients (74%) who were started on
medication were male and White/Caucasian. A BAV was diagnosed in 40%,
MFS was diagnosed in 28%, isolated AoD in 21%, TS in 4%, and LDS in
4%.
Thirty patients had genetic testing, of which 20 (67%) had a genetic
anomaly identified (Table 2). Family history was significant in 40% of
patients including AoD, aortic dissection, or vascular aneurysm.
Majority of patients were started on Losartan (51%), Atenolol (32%),
Metoprolol ( 13%), and Lisinopril (4%). Four patients (9%) had a
documented diagnosis of hypertension at the time of initiation of
medication for AoD. Only one patient was not on medication at the time
they underwent surgery.