CONCLUSIONS
In this study, we extended our prior work on IFC malposition1,3 by assessing the effect of preoperative anatomic and surgical technique on CF-LVAD IFC malposition, and the effects of malposition on LV unloading and outcomes. We found that the LTHS technique was associated with a lower total malposition magnitude, and that a more laterally and posteriorly displaced apex and a more steeply inclined apex-LVOT axis portend malposition. Post-LVAD, we found that IFC malposition was associated with lower LVAD FI and with increased 30-day and overall HFRAs. Careful surgical planning and attention to intraoperative IFC positioning may mitigate these risks. Further study in a large, multicenter cohort is warranted.