Thyroid nodules are often incidentally noted on imaging studies with an estimated incidence of 25% on neck CT scan. The presence of a PET-avid thyroid nodule, especially in a patient with a history of malignancy, should prompt evaluation with fine-needle aspiration to evaluate for malignancy given the high probability.
We present an adult patient with Crouzon syndrome manifesting with facial deformities and panhypopituitarism. Crouzon syndrome is a rare, autosomal dominant genetic disorder characterized by facial bone deformities, such as a prominent nose, frontal bossing, and ocular proptosis, as well as headaches, seizures, and developmental delay.
Adrenocortical carcinoma (ACC) is one of the causes for large retroperitoneal masses. Symptoms could be minimal if the tumor is not hormonally active. We describe a case with only dull flank pain as an initial presentation. Imaging studies confirmed a large, irregular mass with central necrosis and calcification.