Sars-Cov-2 infection
The viral infection caused by the new Sars-Cov-2 (COVID-19), recorded
its first cases in China at the end of 2019, and within a few months it
became a global pandemic. At the time of writing there were 4.71 million
infected cases and 315,000 deaths with over 250 countries affected. (1)
In most cases, COVID-19 infection is a mild disease, and resolves
spontaneously with symptoms such as weakness, nausea, fever lines, while
some people develop a severe infection characterized by a rapid decline
in lung function and breathing difficulties. A minority of patients
develop a generalized inflammatory state caused by a cytokinic storm
responsible for multi-organ dysfunction, which can rapidly cause the
death of the patient. To date, there are no direct antivirals and
effective vaccines against Sars-Cov-2. (2)