Sars-Cov-2 infection
The viral infection caused by the new Sars-Cov-2 (COVID-19), recorded its first cases in China at the end of 2019, and within a few months it became a global pandemic. At the time of writing there were 4.71 million infected cases and 315,000 deaths with over 250 countries affected. (1) In most cases, COVID-19 infection is a mild disease, and resolves spontaneously with symptoms such as weakness, nausea, fever lines, while some people develop a severe infection characterized by a rapid decline in lung function and breathing difficulties. A minority of patients develop a generalized inflammatory state caused by a cytokinic storm responsible for multi-organ dysfunction, which can rapidly cause the death of the patient. To date, there are no direct antivirals and effective vaccines against Sars-Cov-2. (2)