Pregnancy Outcomes in FET Cycles
During the study, 144 women in the
PPOS group and 123 women in the antagonist group complete their first
FET. Method of endometrial preparation was different between the two
groups. A higher proportion of women used mild stimulation in the PPOS
group, while more patients underwent natural cycles in the antagonist
group. The number of top quality of embryos after thawing, number of
embryos transferred, and endometrial
thickness were similar between two
groups (Table 2).
Both
groups showed comparable ongoing
pregnancy, clinical pregnancy, implantation rates, miscarriage, multiple
pregnancy and ectopic pregnancy rates.
A
multivariate logistic regression
using the enter method by the women’s age,
duration
of infertility, stimulation protocol (PPOS / antagonist), insemination
method, antral follicle count, basal FSH level, FSH/HMG dosage /
duration, serum estradiol levels on the day of hCG, number of oocytes
obtained, endometrial thickness, methods of endometrial
preparation, number of (top
quality) embryos replaced revealed that
only the stimulation
protocol (OR=2.277, 95% CI:
1.009-5.138)
and
number of embryos replaced (OR=3.245, 95% CI: 1.259-8.366) predicted
the ongoing pregnancy rate of IVF
(Table 3). The result of
multivariate analysis showed the
pregnancy outcome in the antagonist group was favored.