Data selection
Protein sequences with available Uniprot identifiers and known activity against PET or PUR were downloaded from the Plastics Microbial Biodegradation Database 14 (PMBD, http://pmbd.genome-mining.cn/home/) and NCBI GenBank. Based on available biochemical and/or structural data, in total 44 protein sequences were selected from the PMBD, with 34 and 10 Uniprot identifiers for PET and PUR activity, respectively (as of November 2021).