TABLE 2 The overall effect of Omega-3 Fatty Acid, γ-Linolenic Acid and Antioxidant Supplementation in critically ill patients TABLE 2 The overall effect of Omega-3 Fatty Acid, γ-Linolenic Acid and Antioxidant Supplementation in critically ill patients TABLE 2 The overall effect of Omega-3 Fatty Acid, γ-Linolenic Acid and Antioxidant Supplementation in critically ill patients TABLE 2 The overall effect of Omega-3 Fatty Acid, γ-Linolenic Acid and Antioxidant Supplementation in critically ill patients TABLE 2 The overall effect of Omega-3 Fatty Acid, γ-Linolenic Acid and Antioxidant Supplementation in critically ill patients TABLE 2 The overall effect of Omega-3 Fatty Acid, γ-Linolenic Acid and Antioxidant Supplementation in critically ill patients TABLE 2 The overall effect of Omega-3 Fatty Acid, γ-Linolenic Acid and Antioxidant Supplementation in critically ill patients TABLE 2 The overall effect of Omega-3 Fatty Acid, γ-Linolenic Acid and Antioxidant Supplementation in critically ill patients
Meta-analysis Meta-analysis Heterogeneity Heterogeneity Heterogeneity
Outcomes
Num. Studies
Num. Participants WMD1 (95%CI) P effect Q statistic
P within group
I2 (%)
Length of hospital stay (day)
\sout 5 534 -2.12 (-7.56, 3.31) 0.44 36.96
< 0.001
89.2
Duration of ICU stay (day)
8
901 -2.97 (-5.60, -0.35) 0.03 62.55
< 0.001
\sout 88.8
ICU- free days (day)
5
735 4.06 (0.02, 8.09) 0.049 39.63
< 0.001
\sout 89.9
Duration of mechanical ventilation (day)
7
667 -2.20 (-4.29, -0.10) 0.04 25.86
< 0.001
\sout 76.8
Ventilator- free days (day)
4
629 3.24 (-2.20, 8.85) 0.24 31.74
< 0.001
\sout 90.5
Level of oxygenation (PaO2/FiO2)
6
709 27.40 (-7.84, 62.65) 0.13 55.44
< 0.001
\sout 91
SOFA and MOD score
3
190 -0.42 (-0.74, -0.11)* 0.008 2.24 \sout 0.33 \sout 10.8
Overall 28 days mortality
9
1104 0.74 (0.58, 0.91)** < 0.001 7.77 \sout 0.46 \sout 0.0
1Data are pooled standardized mean differences (95% CIs) by a random-effects model. * For SOFA and MOD score Hedge’s g was calculated. ** For overall 28 days mortality effect size is rr(95%CI). ICU, intensive care unit; 1Data are pooled standardized mean differences (95% CIs) by a random-effects model. * For SOFA and MOD score Hedge’s g was calculated. ** For overall 28 days mortality effect size is rr(95%CI). ICU, intensive care unit; 1Data are pooled standardized mean differences (95% CIs) by a random-effects model. * For SOFA and MOD score Hedge’s g was calculated. ** For overall 28 days mortality effect size is rr(95%CI). ICU, intensive care unit; 1Data are pooled standardized mean differences (95% CIs) by a random-effects model. * For SOFA and MOD score Hedge’s g was calculated. ** For overall 28 days mortality effect size is rr(95%CI). ICU, intensive care unit; 1Data are pooled standardized mean differences (95% CIs) by a random-effects model. * For SOFA and MOD score Hedge’s g was calculated. ** For overall 28 days mortality effect size is rr(95%CI). ICU, intensive care unit; 1Data are pooled standardized mean differences (95% CIs) by a random-effects model. * For SOFA and MOD score Hedge’s g was calculated. ** For overall 28 days mortality effect size is rr(95%CI). ICU, intensive care unit; 1Data are pooled standardized mean differences (95% CIs) by a random-effects model. * For SOFA and MOD score Hedge’s g was calculated. ** For overall 28 days mortality effect size is rr(95%CI). ICU, intensive care unit; 1Data are pooled standardized mean differences (95% CIs) by a random-effects model. * For SOFA and MOD score Hedge’s g was calculated. ** For overall 28 days mortality effect size is rr(95%CI). ICU, intensive care unit;