Figure 4 The distances of the ligand with residues of wild-type and W6.48L mutant receptor
The distances of ligand with A. Y7.43 in wild type and W6.48L mutant MOR bound with morphine; B. Y7.43 in wild type and W6.48L mutant MOR bound with sufentanil; C. Y7.43 in wild type and W6.48L mutant MOR bound with fentanyl; D. W6.48 in wild type and W6.48L mutant MOR bound with morphine; E. W6.48 in wild type and mutant (W6.48L) MOR bound with sufentanil; F W6.48L in wild type and W6.48L mutant MOR bound with fentanyl; The distances between Y7.43 and W6.48 in G. wild type and mutant (W6.48L) MOR bound with morphine; H. wild type and mutant (W6.48L) MOR bound with sufentanil; I. wild type and mutant (W6.48L) MOR bound with fentanyl; The Y7.43 and W6.48 distances distribution of distances in J. wild type and mutant (W6.48L) MOR bound with morphine; K. wild type and mutant (W6.48L) MOR bound with sufentanil; L. wild type and mutant (W6.48L) MOR bound with fentanyl.