1. Structure of μ-opioid receptor
  2. Ramachandran plo
Figure S2 The time evolved potential energy and RMSD
The potential energy of eight systems: A. wild type apo system, B. morphine and active MOR system, C. sulfentanil and active MOR system, D. fentanyl and active MOR system, E. MOR-W6.48L system, F. morphine and active MOR-W6.48L system, G. sulfentanil and active MOR-W6.48L system, H. fentanyl and active MOR-W6.48L system; The RMSD of wild type systems: I. protein, J. ligand; The RMSD of mutational systems: K. protein, L. ligand.