Details of Ethics Approval
The study was approved by the Institutional Review Board of the First
Affiliated Hospital of Zhengzhou University (2018-KY-41; date of
approval 14 August 2018). All patients provided written informed
consent.
Funding: sponsored by Program for Science and Technology
Innovation Talents in Henan Province (2018JR0004) and ZhongYuan thousand
talents program-the Zhongyuan eminent doctor in Henan province
(ZYQR201810107) and National Natural Science Foundation of China
(31670844).