1. Patient characteristics and complications of CNS
A total of 356 patients with early-stage cervical cancer underwent SLNB
with CNS injection, followed by standard treatment. The time required
for SLN mapping was 8.7 ± 1.5 min (range: 4.5–15.0 min). Adverse
reactions to CNS were rare, and no patient exhibited an anaphylactic
reaction or serious adverse events related to CNS. A low-grade fever
occasionally occurred following injection intra-operatively (1.12%);
however, it did not require special treatment. Patient demographics and
tumour characteristics are summarised in Table 1. The mean age of the
patients was 46 years (range: 23–68 years). Histology primarily
indicated squamous carcinoma (89.04%).