Maternal Characteristics |
|
|
|
|
|
|
|
Maternal age (years) |
32 (29, 35) |
34 (31, 39) |
32 (29, 35) |
32 (29,
35) |
32 (29, 35) |
|
|
20-29 |
7269 (30.6) |
129 (16.9) |
4107 (31.6) |
2417 (30.5) |
616
(30.1) |
520.688 |
<0.001 |
30-34 |
9640 (40.6) |
257 (33.7) |
5289 (40.7) |
3217 (40.7) |
877
(42.9) |
|
|
35-37 |
3790 (16.0) |
132 (17.3) |
1956 (15.0) |
1367 (17.3) |
335
(16.4) |
|
|
38-39 |
1297 (5.5) |
75 (9.8) |
644 (5.0) |
464 (5.9) |
114 (5.6) |
|
|
40-42 |
1084 (4.6) |
71 (9.3) |
603 (4.6) |
329 (4.2) |
81 (4.0) |
|
|
>42 |
646 (2.7) |
99 (13.0) |
405 (3.1) |
119 (1.5) |
23
(1.1) |
|
|
Body Mass Index (BMI) |
21.6 (19.8, 24.0) |
21.5 (19.6, 23.9) |
21.5
(19.6, 23.7) |
22.0 (20.0, 24.4) |
21.5 (19.7, 23.8) |
|
|
Underweight (BMI<18.5) |
1914 (8.1) |
62 (8.1) |
1128 (8.7) |
554 (7.0) |
170 (8.3) |
87.861 |
<0.001 |
Fitting (18.5≤BMI<24) |
11474 (48.4) |
338 (44.3) |
6259
(48.1) |
3862 (48.8) |
1015 (49.6) |
|
|
Overweight (24≤BMI<27) |
2940 (12.4) |
84 (11.0) |
1480 (11.4) |
1132 (14.3) |
244 (11.9) |
|
|
Obesity (BMI≥27) |
1571 (6.6) |
39 (5.1) |
744 (5.7) |
654 (8.3) |
134
(6.5) |
|
|
Missing value |
5827 (24.6) |
240 (31.5) |
3393 (26.1) |
1711 (21.6) |
483 (23.6) |
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|
Infertility type |
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|
|
|
|
|
|
Primary infertility |
14463 (61.0) |
402 (52.7) |
8034 (61.8) |
4731
(59.8) |
1296 (63.3) |
33.535 |
<0.001 |
Secondary infertility |
9026 (38.0) |
343 (45.0) |
4828 (37.1) |
3125
(39.5) |
730 (35.7) |
|
|
Missing value |
237 (1.0) |
18 (2.4) |
142 (1.1) |
57 (0.7) |
20 (1.0) |
|
|
Cause of infertility |
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|
|
|
|
|
|
Tubal |
8730 (36.8) |
259 (33.9) |
5075 (39.0) |
2539 (32.1) |
857
(41.9) |
128.751 |
<0.001 |
Ovulatory |
5575 (23.5) |
201 (26.3) |
3019 (23.2) |
1801 (22.8) |
554
(27.1) |
20.990 |
<0.001 |
Endometriosis |
1455 (6.1) |
65 (8.5) |
835 (6.4) |
440 (5.6) |
115
(5.6) |
14.860 |
0.002 |
Male factor |
9023 (38.0) |
261 (34.2) |
5025 (38.6) |
3018 (38.1) |
719
(35.1) |
14.081 |
0.003 |
Unexplained |
5136 (21.6) |
183 (24.0) |
2456 (18.9) |
2138 (27.0) |
359
(17.5) |
215.792 |
<0.001 |
Duration of infertility (years) |
4 (2, 6) |
4 (2, 6) |
4 (2, 6) |
4 (2,
6) |
4 (2, 6) |
|
|
≤4 |
14142 (59.6) |
4234 (55.6) |
7964 (61.2) |
4584 (57.9) |
1170
(57.2) |
29.042 |
<0.001 |
>4 |
8957 (37.8) |
308 (40.4) |
4726 (36.3) |
3104 (39.2) |
819 (40.0) |
|
|
Missing value |
627 (2.6) |
31 (4.1) |
314 (2.4) |
225 (2.8) |
57 (2.8) |
|
|
Type of fertilization in current cycle |
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|
|
|
|
|
|
IVF |
12113 (51.1) |
437 (57.3) |
7074 (54.4) |
3458 (43.7) |
1144
(55.9) |
296.204 |
<0.001 |
ICSI |
10574 (44.6) |
304 (39.9) |
5423 (41.7) |
4075 (51.5) |
771
(37.7) |
|
|
IVF+ICSI |
1039 (4.4) |
21 (2.8) |
507 (3.9) |
380 (4.8) |
131 (6.4) |
|
|
Previous ART cycles |
3 (2, 4) |
2 (1, 3) |
1 (1, 2) |
2 (1, 3) |
2 (2,
4) |
|
|
0-1 cycles |
10710 (45.1) |
217 (28.5) |
6307 (48.5) |
3727 (47.1) |
458
(22.4) |
768.355 |
<0.001 |
2-3 cycles |
8590 (36.2) |
328 (43.0) |
4538 (34.9) |
2754 (34.8) |
970
(47.4) |
|
|
4-5 cycles |
2185 (9.2) |
85 (11.2) |
923 (7.1) |
831 (10.5) |
346
(16.9) |
|
|
≥6 cycles |
804 (3.4) |
49 (6.4) |
299 (2.3) |
317 (4.0) |
139 (6.8) |
|
|
Missing value |
1437 (6.1) |
83 (10.9) |
936 (7.2) |
285 (3.6) |
133
(6.5) |
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|
Maternal & Neonatal Outcomes |
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Biochemical pregnancy |
11427 (48.2) |
184 (24.1) |
6077 (46.7) |
3957
(50.0) |
1209 (59.1) |
296.037 |
<0.001 |
Clinical pregnancy |
10237 (43.1) |
164 (21.5) |
5481 (42.1) |
3507
(44.3) |
1085 (53.0) |
237.023 |
<0.001 |
*Monozygotic twins |
151 (1.5) |
3 (1.8) |
47 (0.9) |
79 (2.3) |
22 (2.0) |
31.668@
|
<0.001@
|
*Miscarriage |
1687 (16.5) |
39 (23.8) |
786 (14.3) |
632 (18.0) |
230 (21.2) |
48.180 |
<0.001 |
*Maternal complication |
968 (9.5) |
12 (7.1) |
515
(9.4) |
312 (8.9) |
129 (11.9) |
9.686 |
0.021 |
Live birth |
6368 (26.8) |
90 (11.8) |
3771 (29.0) |
1819 (23.0) |
688
(33.6) |
226.611 |
<0.001 |
∆Twin birth |
1116 (17.5) |
0 (0.0) |
883 (23.4) |
34
(1.9) |
199 (28.9) |
479.969 |
<0.001 |
∆Preterm birth |
936 (14.7) |
6 (6.7) |
609 (16.1) |
175 (9.6) |
146 (21.2) |
71.715 |
<0.001 |
∆Low birth weight |
776 (12.2) |
3 (3.3) |
559 (14.8) |
92 (5.1) |
122 (17.7) |
137.261 |
<0.001 |
∆SGA |
362 (5.7) |
4 (4.4) |
267 (7.1) |
55 (3.0) |
36
(5.2) |
38.245 |
<0.001 |